SCHEMBL4624434

SCHEMBL4624434

O=P(Oc1cc[c]cc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
SRC P12931 1/20 0.50
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HTT P42858 2/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA4 P22748 2/20 0.40
CA5A P35218 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA5B Q9Y2D0 2/20 0.40
LMNA P02545 2/20 0.38
RECQL P46063 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphenyl Phosphate SCHEMBL1028391 0.89 SRC (0.61) L3MBTL1TDP1SRCCYP3A4TSHR
SCHEMBL4624431 0.87 L3MBTL1 (0.46) L3MBTL1TDP1SRCCYP3A4TSHR
Triphenyl Phosphate SCHEMBL28761613 0.86 SRC (0.64) L3MBTL1TDP1SRCCYP3A4TSHR
Triphenyl Phosphate SCHEMBL28557783 0.86 SRC (0.64) L3MBTL1TDP1SRCCYP3A4TSHR
Triphenyl Phosphate SCHEMBL483692 0.86 SRC (0.64) L3MBTL1TDP1SRCCYP3A4TSHR
Triphenyl Phosphate SCHEMBL18116 0.86 SRC (0.64) L3MBTL1TDP1SRCCYP3A4TSHR
Triphenyl Phosphate SCHEMBL1924512 0.84 SRC (0.61) L3MBTL1TDP1SRCCYP3A4TSHR
SCHEMBL10015245 0.84 CYP3A4 (0.61) L3MBTL1TDP1SRCCYP3A4TSHR
Triphenyl Phosphate SCHEMBL15815456 0.84 SRC (0.61) L3MBTL1TDP1SRCCYP3A4TSHR
Triphenyl Phosphate SCHEMBL2530073 0.84 SRC (0.61) L3MBTL1TDP1SRCCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1191029-B1 PROCESS FOR THE PREPARATION OF CONDENSED PHOSPHORIC ESTERS DAIHACHI CHEM IND (JP) 2008-05-21 EP claimed
EP-1191029-B1 PROCESS FOR THE PREPARATION OF CONDENSED PHOSPHORIC ESTERS DAIHACHI CHEM IND (JP) 2008-05-21 EP disclosed