⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624876 | 0.82 | — | — | |
| SCHEMBL23656184 | 0.81 | SIGMAR1 (0.34) | — | |
| SCHEMBL3656009 | 0.78 | SIGMAR1 (0.43) | — | |
| SCHEMBL30027858 | 0.75 | SIGMAR1 (0.41) | — | |
| SCHEMBL23470344 | 0.75 | SIGMAR1 (0.36) | — | |
| SCHEMBL19605733 | 0.75 | SIGMAR1 (0.50) | — | |
| Isoquinoline SCHEMBL28392791 | 0.74 | CA1 (0.39) | — | |
| Isoquinoline SCHEMBL1308876 | 0.74 | CA1 (0.39) | — | |
| Isoquinoline SCHEMBL1310260 | 0.74 | CA1 (0.39) | — | |
| SCHEMBL14965050 | 0.73 | SIGMAR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617198-B1 | GUANIDINE DERIVATIVE | LUNAN PHARMACEUTICAL GROUP CORP (CN) | 2023-10-25 | — | — | EP | claimed |
| EP-1792605-A1 | Use of at least a cationic cyanine derivative for use in hair dyeing, composition containg it process of treating keratinic fibres using the same composition, kit and use thereof | L'Oréal (FR) | 2007-06-06 | — | — | EP | claimed |
| EP-4448526-A1 | PYRAZOLOPYRAZINE COMPOUNDS AS SHP2 INHIBITORS | GENZYME CORPORATION (US) | 2024-10-23 | — | — | EP | disclosed |
| US-20240270759-A1 | Preparation of SHP2 phosphatase inhibitors and its applications | YA THERAPEUTICS INC (CN) | 2024-08-15 | — | — | US | disclosed |
| US-11912714-B2 | Spiropyrrolidine derived antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11858945-B2 | Alkyne-containing antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230365525-A1 | ANTIVIRAL COMPOUNDS | ENANTA PHARMACEUTICALS, INC. | 2023-11-16 | — | — | US | disclosed |
| US-11809079-B2 | Photosensitive resin composition, polyimide production method, and semiconductor device | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-11-07 | — | — | US | disclosed |
| EP-3617198-B1 | GUANIDINE DERIVATIVE | LUNAN PHARMACEUTICAL GROUP CORP (CN) | 2023-10-25 | — | — | EP | disclosed |
| US-20230331673-A1 | COMPOSITION OF COMPOUNDS THAT MODULATE CELL METABOLISM AND METHODS OF USE | CRESCENTA BIOSCIENCES (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230331734-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-10-19 | — | — | US | disclosed |
| EP-0327239-B1 | 1-carbacephalosporin antibiotics | LILLY CO ELI (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5019571-A | 1-carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| US-4902707-A | Bicyclic pyrazolidinones, compositions and use | ELI LILLY AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0327239-A1 | 1-carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0203722-A1 | Bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |
| CN-86102877-A | The method for preparing bicyclic pyrazolidinones | — | 1986-10-29 | — | — | CN | disclosed |