Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4624573 | 1.00 | — | — | |
| Carbamic Acid SCHEMBL1422615 | 0.87 | — | — | |
| Acetic Acid SCHEMBL10773161 | 0.84 | FFAR3 (0.54) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acrylic Acid SCHEMBL973151 | 0.84 | — | — | |
| Acetic Acid SCHEMBL5918793 | 0.84 | FFAR3 (0.54) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acetic Acid SCHEMBL1054733 | 0.84 | — | — | |
| Acetic Acid SCHEMBL292254 | 0.84 | FFAR3 (0.54) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acetic Acid SCHEMBL2259927 | 0.84 | FFAR3 (0.54) | LMNATSHRALDH1A1FGFR4CA1 | |
| Urea SCHEMBL329207 | 0.82 | — | — | |
| Acrylic Acid SCHEMBL9125301 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846481-B1 | POLYAMINE-COATED SUPERABSORBENT POLYMERS | BASF SE (DE) | 2008-10-08 | — | — | EP | claimed |
| US-20080114129-A1 | Base polymer with a surface coating of a polyammonium carbonate; an inorganic salt | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-15 | — | — | US | claimed |
| EP-1846481-A1 | POLYAMINE-COATED SUPERABSORBENT POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2007-10-24 | — | — | EP | claimed |
| EP-1690555-A2 | Absorbent articles comprising polyamine-coated superabsorbent polymers | Kimberly Clark Worldwide, Inc. (US) | 2006-08-16 | — | — | EP | claimed |
| WO-2006082189-A1 | POLYAMINE-COATED SUPERABSORBENT POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-10 | — | — | WO | claimed |
| US-20060173431-A1 | Absorbent articles comprising polyamine-coated superabsorbent polymers | KIMBERLY-CLARK WORLDWIDE, INC. | 2006-08-03 | — | — | US | claimed |
| EP-1846481-B1 | POLYAMINE-COATED SUPERABSORBENT POLYMERS | BASF SE (DE) | 2008-10-08 | — | — | EP | disclosed |
| US-20080114129-A1 | Base polymer with a surface coating of a polyammonium carbonate; an inorganic salt | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-15 | — | — | US | disclosed |
| EP-1846481-A1 | POLYAMINE-COATED SUPERABSORBENT POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2007-10-24 | — | — | EP | disclosed |
| EP-1690555-A2 | Absorbent articles comprising polyamine-coated superabsorbent polymers | Kimberly Clark Worldwide, Inc. (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2006082189-A1 | POLYAMINE-COATED SUPERABSORBENT POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173431-A1 | Absorbent articles comprising polyamine-coated superabsorbent polymers | KIMBERLY-CLARK WORLDWIDE, INC. | 2006-08-03 | — | — | US | disclosed |