SCHEMBL4624717

SCHEMBL4624717

Cc1cc(C)c(C(=O)P(=O)(C(=O)c2c(C)cc(C)cc2C)c2ccc(OCCC(C)C)cc2OCCC(C)C)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.42
EPHX2 P34913 1/20 0.40
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NR1H4 Q96RI1 2/20 0.37
GALR3 O60755 1/20 0.37
HSP90AA1 P07900 1/20 0.37
HTT P42858 2/20 0.37
ITGB1 P05556 1/20 0.37
ITGA4 P13612 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GAA P10253 2/20 0.36
PDK2 Q15119 1/20 0.36
ALOX12 P18054 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
S1PR1 P21453 1/20 0.35
S1PR5 Q9H228 1/20 0.35
MMP2 P08253 1/20 0.35
MMP13 P45452 1/20 0.35
INPPL1 O15357 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29660657 1.00 MAPK1 (0.42) MAPK1EPHX2TP53SMN1; SMN2NR1H4
SCHEMBL7550813 0.92 MAPK1 (0.41) MAPK1EPHX2TP53SMN1; SMN2NR1H4
SCHEMBL4629642 0.87 FOS (0.36) TP53SMN1; SMN2NR1H4HTTITGB1
SCHEMBL29660692 0.87 FOS (0.36) TP53SMN1; SMN2NR1H4HTTITGB1
SCHEMBL444479 0.87 ITGB1 (0.46) TP53ITGB1ITGA4MMP13INPPL1
SCHEMBL29389044 0.87 ITGB1 (0.46) TP53ITGB1ITGA4MMP13INPPL1
SCHEMBL150337 0.85 ITGB1 (0.49) TP53ITGB1ITGA4
SCHEMBL4625245 0.84 ITGB1 (0.48) TP53ITGB1ITGA4
SCHEMBL4624645 0.84 ITGB1 (0.48) TP53ITGB1ITGA4
SCHEMBL29660598 0.84 ITGB1 (0.48) TP53ITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1215044-B1 A laser engravable flexographic printing element and a method for forming a printing plate from the element DU PONT (US) 2008-05-21 EP claimed
US-6737216-B2 TO FORM A RELIEF SURFACE E.I. DU PONT DE NEMOURS AND COMPANY 2004-05-18 US claimed
US-20020123003-A1 To form a relief surface E.I. DU PONT DE NEMOURS AND COMPANY 2002-09-05 US claimed
EP-1215044-A2 A laser engravable flexographic printing element and a method for forming a printing plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-19 EP claimed
CN-110114376-B Curable composition, method for producing cured product, cured product thereof, and adhesive using same 株式会社ADEKA 2022-06-14 CN disclosed
EP-3339331-B1 COMPOSITION ADEKA CORP (JP) 2022-02-16 EP disclosed
EP-3339331-A1 COMPOSITION Adeka Corporation (JP) 2018-06-27 EP disclosed
EP-1215044-B1 A laser engravable flexographic printing element and a method for forming a printing plate from the element DU PONT (US) 2008-05-21 EP disclosed
US-6900280-B2 Acid macromonomers and their method of preparation CIBA SPECIALTY CHEMICALS CORP. (US) 2005-05-31 US disclosed
US-20040072978-A1 Compositions of acid macromonomers and their method of preparation CIBA SPECIALTY CHEMICALS CORP. 2004-04-15 US disclosed
EP-1392736-A2 ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION Ciba SC Holding AG (CH) 2004-03-03 EP disclosed
US-6576684-B1 Ammonium, phosphonium or sulfonium containing oligomers or polymers; controlled molecular weight, low polydispersity and a vinyl or dienyl end group; polymeric precursors and addi-tives CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-10 US disclosed
EP-0961787-B1 (CO)POLYMERS BY PHOTOPOLYMERIZATION CIBA SC HOLDING AG (CH) 2002-05-22 EP disclosed
EP-1112288-A1 THERMAL- AND PHOTOINITIATED RADICAL POLYMERIZATION IN THE PRESENCE OF AN ADDITION FRAGMENTATION AGENT Ciba SC Holding AG (CH) 2001-07-04 EP disclosed
US-6251962-B1 ACRYLATE POLYMER CIBA SPECIALTY CHEMICALS CORPORATION 2001-06-26 US disclosed
WO-2000011041-A1 THERMAL- AND PHOTOINITIATED RADICAL POLYMERIZATION IN THE PRESENCE OF AN ADDITION FRAGMENTATION AGENT CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-02 WO disclosed
EP-0961787-A1 (CO)POLYMERS BY PHOTOPOLYMERIZATION Ciba SC Holding AG (CH) 1999-12-08 EP disclosed
US-5965776-A PHOTOINITIATORS FOR THE PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED COMPOUNDS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-10-12 US disclosed
WO-1998037105-A1 (CO)POLYMERS BY PHOTOPOLYMERIZATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-08-27 WO disclosed
US-5767169-A STORAGE STABLE, NONHYDROLYZING CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-16 US disclosed