Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360928 | 0.77 | ATM (0.39) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL2444831 | 0.77 | ATM (0.39) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL2444825 | 0.77 | ATM (0.39) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL29367523 | 0.77 | ATM (0.39) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL3114118 | 0.77 | ATM (0.39) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL2471057 | 0.77 | ATM (0.39) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL29369392 | 0.77 | ATM (0.39) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL432619 | 0.75 | CCR9 (0.41) | CYP3A4CYP3A5POLBMAPT | |
| SCHEMBL15262991 | 0.74 | CYP19A1 (0.45) | CYP19A1CYP3A4CYP3A5POLB | |
| SCHEMBL27041081 | 0.74 | ACP1 (0.39) | CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130252972-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252972-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252972-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-26 | — | — | US | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252972-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | NOX1, NOX5, NOS1 | CYP19A1 1573/4885CYP3A4 50/4885CYP3A5 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.