Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | CCKBR | P32239 | 6/20 | 0.57 |
| ▸ | CCKAR | P32238 | 5/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042943 | 0.92 | CYP3A4 (0.60) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9039819 | 0.90 | CYP3A4 (0.57) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9041762 | 0.90 | CYP3A4 (0.58) | CYP3A4MAPTTSHRCCKBR | |
| SCHEMBL9037769 | 0.90 | CYP3A4 (0.58) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9039138 | 0.89 | CYP3A4 (0.57) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9038073 | 0.87 | CYP3A4 (0.53) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9039602 | 0.86 | CCKBR (0.57) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9039704 | 0.85 | CCKBR (0.60) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9040863 | 0.85 | CCKBR (0.61) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9038502 | 0.85 | CYP3A4 (0.53) | CYP3A4MAPTTSHRCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008354-B1 | IMMEDIATELY DISINTEGRABLE MEDICINAL COMPOSITIONS | ASTELLAS PHARMA INC (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-7189415-B2 | Rapidly disintegrable pharmaceutical composition | ASTELLAS PHARMA INC. (JP) | 2007-03-13 | — | — | US | disclosed |
| US-20070014856-A1 | Rapidly disintegrable pharmaceutical composition | ASTELLAS PHARMA INC. | 2007-01-18 | — | — | US | disclosed |
| US-6899899-B2 | Rapidly disintegrable pharmaceutical composition | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20050095289-A1 | Rapidly disintegrable pharmaceutical composition | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2005-05-05 | — | — | US | disclosed |
| US-20030003146-A1 | Rapidly disintegrable pharmaceutical composition | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2003-01-02 | — | — | US | disclosed |
| US-20020031547-A1 | IMMEDIATELY DISINTEGRABLE MEDICINAL COMPOSITION | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2002-03-14 | — | — | US | disclosed |
| EP-1008354-A1 | IMMEDIATELY DISINTEGRABLE MEDICINAL COMPOSITIONS | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-06-14 | — | — | EP | disclosed |
| EP-0703222-A1 | 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |