Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.50 |
| ▸ | DPP4 | P27487 | 5/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121270 | 0.91 | DPP4 (0.42) | GPR119DPP4DPP8 | |
| SCHEMBL1721232 | 0.89 | DPP4 (0.48) | GPR119DPP4DPP8FAAH | |
| SCHEMBL148984 | 0.83 | GPR119 (0.40) | GPR119DPP4DPP8 | |
| SCHEMBL121324 | 0.82 | DPP4 (0.41) | GPR119DPP4DPP8FAAH | |
| SCHEMBL611501 | 0.79 | DPP4 (0.50) | GPR119DPP4DPP8 | |
| SCHEMBL148610 | 0.77 | GPR119 (0.39) | GPR119 | |
| SCHEMBL149427 | 0.76 | DPP4 (0.43) | GPR119DPP4DPP8 | |
| SCHEMBL149426 | 0.76 | DPP4 (0.43) | GPR119DPP4DPP8 | |
| SCHEMBL121107 | 0.76 | DPP4 (0.43) | GPR119DPP4DPP8 | |
| SCHEMBL120032 | 0.76 | GPR119 (0.42) | GPR119DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |