Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625260 | 1.00 | GABRR1 (0.41) | GABRR1CPB2GSRSLC1A3SLC1A2 | |
| SCHEMBL7281760 | 0.81 | CPB2 (0.42) | GABRR1CPB2GSRSLC1A3SLC1A2 | |
| SCHEMBL7281767 | 0.81 | CPB2 (0.42) | GABRR1CPB2GSRSLC1A3SLC1A2 | |
| SCHEMBL6009873 | 0.79 | CPB2 (0.38) | GABRR1CPB2GSRRNPEP | |
| SCHEMBL17872153 | 0.79 | CPB2 (0.44) | GABRR1CPB2GSRRNPEPBLM | |
| SCHEMBL17872154 | 0.79 | CPB2 (0.44) | GABRR1CPB2GSRRNPEPBLM | |
| SCHEMBL25238647 | 0.76 | CPB2 (0.45) | GABRR1CPB2GSRRNPEPBLM | |
| SCHEMBL527672 | 0.76 | CPB2 (0.45) | GABRR1CPB2GSRRNPEPBLM | |
| SCHEMBL7323886 | 0.76 | CPB2 (0.45) | GABRR1CPB2GSRRNPEPBLM | |
| SCHEMBL4298060 | 0.76 | GSR (0.48) | GABRR1CPB2GSRSLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101395173-B | Template-fixed peptidomimetics with antimicrobial activity | POLYPHOR LTD | 2013-03-13 | — | — | CN | disclosed |
| CN-1802385-B | Template-fixed beta-hairpin peptidomimetics with CXCR4 antagonizing activity | POLYPHOR AG | 2011-11-09 | — | — | CN | disclosed |
| CN-101395173-A | Template-fixed peptidomimetics with antimicrobial activity | POLYPHOR LTD (CH) | 2009-03-25 | — | — | CN | disclosed |
| EP-1979374-A2 | TEMPLATE-FIXED PEPTIDOMIMETICS | Polyphor Ltd. (CH) | 2008-10-15 | — | — | EP | disclosed |
| EP-1879911-A1 | DYE CONJUGATES OF TEMPLATE-FIXED PEPTIDOMIMETICS | Polyphor Ltd. (CH) | 2008-01-23 | — | — | EP | disclosed |
| EP-1856140-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | Polyphor Ltd. (CH) | 2007-11-21 | — | — | EP | disclosed |
| WO-2007079605-A2 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIMICROBIAL ACTIVITY | POLYPHOR LTD. (CH) | 2007-07-19 | — | — | WO | disclosed |
| WO-2006117011-A1 | DYE CONJUGATES OF TEMPLATE-FIXED PEPTIDOMIMETICS | POLYPHOR LTD. (CH) | 2006-11-09 | — | — | WO | disclosed |
| WO-2006087001-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | POLYPHOR LTD. (CH) | 2006-08-24 | — | — | WO | disclosed |
| CN-1802385-A | Template-fixed beta-hairpin peptidomimetics with CXCR4 antagonizing activity | POLYPHOR AG (CH) | 2006-07-12 | — | — | CN | disclosed |