⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894851 | 0.71 | — | — | |
| SCHEMBL162387 | 0.71 | — | — | |
| SCHEMBL3398572 | 0.69 | — | — | |
| Phosphoric Acid SCHEMBL8769615 | 0.68 | — | — | |
| Phosphoric Acid SCHEMBL28073838 | 0.65 | — | — | |
| SCHEMBL569381 | 0.65 | — | — | |
| SCHEMBL242547 | 0.65 | LMNA (0.53) | — | |
| SCHEMBL11647720 | 0.65 | LMNA (0.53) | — | |
| Phosphoric Acid SCHEMBL28562163 | 0.65 | TSHR (0.39) | — | |
| SCHEMBL27874570 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775619-A | HYBRIDIZING, BINDING LABEL TO SUPPORT, RELEASING, CLEAVING WITH RESTRICTION ENDONUCLEASE | CHIRON CORPORATION (US) | 1988-10-04 | — | — | US | claimed |
| CN-111893117-B | RNA regulatory oligonucleotides with improved properties for the treatment of duchenne muscular dystrophy and becker muscular dystrophy | 比奥马林技术公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-110257379-B | Oligonucleotides for treating patients with muscular dystrophy | 马林生物科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-110025628-B | RNA-regulatory oligonucleotides with improved properties for the treatment of neuromuscular disorders | 维科医疗有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115161366-A | Novel method for producing oligonucleotides | 葛兰素史克知识产权开发有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-109415399-B | Novel method for producing oligonucleotides | 葛兰素史克知识产权开发有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-112251436-A | RNA-regulated oligonucleotides with improved properties for the treatment of duchenne muscular dystrophy and becker muscular dystrophy | 比奥马林技术公司 | 2021-01-22 | — | — | CN | disclosed |
| CN-111893117-A | RNA-regulated oligonucleotides with improved properties for the treatment of duchenne muscular dystrophy and becker muscular dystrophy | 比奥马林技术公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-104203289-B | RNA-regulatory oligonucleotides with improved properties for the treatment of duchenne muscular dystrophy and becker muscular dystrophy | 比奥马林技术公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-111479923-A | Novel method for producing oligonucleotides | 葛兰素史克知识产权开发有限公司 | 2020-07-31 | — | — | CN | disclosed |
| EP-1296940-B1 | AMIDINE DERIVATIVES AS SELECTIVE ANTAGONISTS OF NMDA RECEPTORS | MERCK SHARP & DOHME (GB) | 2008-07-02 | — | — | EP | disclosed |
| US-6624182-B1 | Method for the treatment of surfaces comprising applying to these surfaces an antimicrobially effective amount of a hydroxyphenylvinyl thiazole of formula antimicrobial, deodorisation and disinfection of the skin, mucosa and hair | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | disclosed |
| US-20030119871-A1 | Amidine derivatives as selective antagonists of ndma receptors | CURTIS NEIL ROY (GB) | 2003-06-26 | — | — | US | disclosed |
| EP-1296940-A1 | AMIDINE DERIVATIVES AS SELECTIVE ANTAGONISTS OF NMDA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001098262-A1 | AMIDINE DERIVATIVES AS SELECTIVE ANTAGONISTS OF NMDA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |