Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750015 | 0.83 | ITGB1 (0.53) | KDM4EALDH1A1BLMMEN1KMT2A | |
| SCHEMBL4626504 | 0.83 | ITGB1 (0.53) | KDM4EALDH1A1BLMMEN1KMT2A | |
| SCHEMBL20809063 | 0.83 | PSMB5 (0.44) | KDM4EALDH1A1BLMMEN1KMT2A | |
| SCHEMBL29982408 | 0.80 | CYP1A2 (0.62) | KDM4EALDH1A1BLMMEN1KMT2A | |
| SCHEMBL8939501 | 0.80 | CYP1A2 (0.62) | KDM4EALDH1A1BLMMEN1KMT2A | |
| SCHEMBL20809049 | 0.78 | MAOA (0.40) | KDM4EALDH1A1BLMMEN1KMT2A | |
| SCHEMBL29746236 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11816557 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| Methane SCHEMBL11817095 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL31038113 | 0.75 | CYP1A2 (0.52) | KDM4EALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501801-B1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF VLA-4 DEPENDENT DISEASES | UCB PHARMA SA (BE) | 2008-01-23 | — | — | EP | disclosed |