Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625314 | 0.91 | HTR1A (0.51) | MEN1KMT2AKDM4EMAPTHTR1A | |
| SCHEMBL2331163 | 0.89 | MEN1 (0.55) | MEN1KMT2AKDM4EMAPTHTR1A | |
| SCHEMBL4625355 | 0.85 | KDM4E (0.50) | MEN1KMT2AKDM4EMAPTHTR1A | |
| SCHEMBL9951781 | 0.84 | MEN1 (0.55) | MEN1KMT2AKDM4EMAPTCCR6 | |
| SCHEMBL4626663 | 0.81 | HTR1A (0.51) | MEN1KMT2AKDM4EMAPTHTR1A | |
| SCHEMBL4624910 | 0.80 | KDM4E (0.52) | MEN1KMT2AKDM4EMAPTCCR6 | |
| SCHEMBL3949886 | 0.77 | MEN1 (0.78) | MEN1KMT2AKDM4EMAPTCCR6 | |
| SCHEMBL4625590 | 0.76 | MEN1 (0.56) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL3318154 | 0.76 | PDGFRB (0.52) | MEN1KMT2AKDM4EMAPTHTR1A | |
| SCHEMBL9951909 | 0.75 | MEN1 (0.55) | MEN1KMT2AKDM4EMAPTCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501801-B1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF VLA-4 DEPENDENT DISEASES | UCB PHARMA SA (BE) | 2008-01-23 | — | — | EP | claimed |