Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462571 | 1.00 | METAP2 (0.42) | METAP2FLT3 | |
| SCHEMBL10284430 | 0.87 | METAP2 (0.56) | METAP2 | |
| SCHEMBL435116 | 0.87 | METAP2 (0.56) | METAP2 | |
| SCHEMBL437312 | 0.81 | METAP2 (0.60) | METAP2 | |
| SCHEMBL14937569 | 0.81 | METAP2 (0.60) | METAP2 | |
| SCHEMBL16290025 | 0.77 | METAP2 (0.54) | METAP2 | |
| SCHEMBL463507 | 0.76 | METAP2 (0.41) | METAP2 | |
| SCHEMBL463508 | 0.76 | METAP2 (0.41) | METAP2 | |
| SCHEMBL16289871 | 0.76 | METAP2 (0.37) | METAP2 | |
| SCHEMBL433251 | 0.73 | METAP2 (0.53) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595988-A1 | TRICYCLIC COMPOUNDS AND METHDS OF MAKING AND USING SAME | Zafgen, Inc. (US) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012012642-A1 | TRICYCLIC COMPOUNDS AND METHDS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2012-01-26 | — | — | WO | disclosed |