Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | PRKCA | P17252 | 1/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.64 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | GMNN | O75496 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28366828 | 1.00 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL29086123 | 1.00 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL28366900 | 1.00 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL4624589 | 1.00 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL4624523 | 1.00 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL28591802 | 1.00 | MAPK1 (0.75) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| Phosphine SCHEMBL28822480 | 0.98 | MAPK1 (0.72) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL2721360 | 0.98 | MAPK1 (0.71) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL250209 | 0.94 | MAPK1 (0.64) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL7783714 | 0.94 | MAPK1 (0.64) | MAPK1MAPTLMNAALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| US-12460099-B2 | Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment | THE PILOT INK CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| EP-3608386-B1 | REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN | PILOT INK CO LTD (JP) | 2025-02-19 | — | — | EP | disclosed |
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| CN-110446770-B | Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same | 百乐墨水株式会社 | 2023-08-08 | — | — | CN | disclosed |
| WO-2023085225-A1 | METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION | 住友化学株式会社 | 2023-05-19 | — | — | WO | disclosed |
| US-20230018132-A1 | REVERSIBLY THERMOCHROMIC AQUEOUS INKJET PRINTER INK COMPOSITION, INKJET PRINTER AND INK CARTRIDGE USING THE SAME | RISO TECHNOLOGIES CORPORATION (JP) | 2023-01-19 | — | — | US | disclosed |
| US-20220169919-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| EP-3950068-A1 | REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME | THE PILOT INK CO., LTD. (JP) | 2022-02-09 | — | — | EP | disclosed |
| CN-113646052-A | Reversible thermal discoloration composition, reversible thermal discoloration microcapsule pigment encapsulating the reversible thermal discoloration composition, and writing instrument using the reversible thermal discoloration microcapsule pigment | 百乐墨水株式会社 | 2021-11-12 | — | — | CN | disclosed |
| EP-1084860-A2 | Thermochromic microencapsulated pigments | THE PILOT INK CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6048387-A | SPECIFIED DIAZARHODAMINE LACTONE DERIVATIVE AS AN ELECTRON-DONATING COLOR-DEVELOPING ORGANIC COMPOUND | THE PILOT INK CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5919404-A | MIXTURE OF COLOR DEVELOPING COMPOUND AND ELECTRON ACCEPTORALKOXYPHENOL COMPOUND | THE PILOT INK CO., LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| EP-0908501-A1 | Reversible thermochromic composition | THE PILOT INK CO., LTD. (JP) | 1999-04-14 | — | — | EP | disclosed |
| US-5879438-A | CONTAINING SPECIFIC ELECTRON ACCEPTING LIGHTFASTNESS PROVIDING AGENT | THE PILOT INK CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5873932-A | BLENDING AN ELECTRON DONATING COMPOUND, AN ELECTRON ACCEPTING COMPOUND, A METACHROMATIC TEMPERATURE ADJUSTER, AN ELECTRON ACCEPTING, LIGHT-FASTNESS PROVIDING AGENT | THE PILOT INK CO., LTD. (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0873881-A1 | Reversible thermochromic compositions | The Pilot Ink CO., Ltd. (JP) | 1998-10-28 | — | — | EP | disclosed |
| EP-0659582-B1 | Reversible thermochromic composition | PILOT INK CO LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| EP-0659582-A1 | Reversible thermochromic composition | THE PILOT INK CO., LTD. (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-4732810-A | CONTAINING ESTERS WITH SPECIFIC MELTING POINT-CLOUD POINT VALVE; LOW HYSTERESIS | PILOT INK CO., LTD. (JP) | 1988-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | MAPK1 235/4885MAPT 1195/4885LMNA 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.