⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3564464 | 0.89 | — | — | |
| SCHEMBL5174488 | 0.86 | HIF1A (0.56) | — | |
| SCHEMBL3568351 | 0.86 | — | — | |
| SCHEMBL27338867 | 0.86 | HIF1A (0.56) | — | |
| Glutaral SCHEMBL27495651 | 0.84 | HIF1A (0.91) | — | |
| Glutaral SCHEMBL1285455 | 0.79 | HIF1A (1.00) | — | |
| SCHEMBL30678319 | 0.79 | — | — | |
| SCHEMBL16816939 | 0.79 | HIF1A (0.82) | — | |
| SCHEMBL30678314 | 0.79 | — | — | |
| Glutaral SCHEMBL836 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158573-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2021-08-12 | — | — | WO | claimed |
| CN-104356087-A | Novel nitric oxide donor type HDAC (histone deacetylase) inhibitor as well as preparation method and medical application thereof | AFFILIATED HOSPITAL OF NANTONG UNIV | 2015-02-18 | — | — | CN | claimed |
| US-20110071173-A1 | IMIDAZOQUINAZOLINE DERIVATIVES AS ANAGRELIDE ANALOGUES FOR THE TREATMENT OF MYELOPROLIFIC DISEASES AND THROMBOTIC DISEASES | SHIRE LLC | 2011-03-24 | — | — | US | claimed |
| CN-109415468-B | Electro-optical polymers | 国立研究开发法人情报通信研究机构 | 2024-06-07 | — | — | CN | disclosed |
| CN-116348767-A | Method for diagnosing tuberculosis and distinguishing active tuberculosis from latent tuberculosis | 西菲伊德公司 | 2023-06-27 | — | — | CN | disclosed |
| US-11390643-B2 | Modified oligonucleotides comprising thiol functions and use thereof for detecting nucleic acids | ETABLISSEMENT FRANÇAIS DU SANG (FR) | 2022-07-19 | — | — | US | disclosed |
| WO-2021158573-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2021-08-12 | — | — | WO | disclosed |
| US-11078229-B2 | Thiol compounds and the use thereof for the synthesis of modified oligonucleotides | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-08-03 | — | — | US | disclosed |
| US-20180265538-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2018-09-20 | — | — | US | disclosed |
| US-9896473-B2 | Thiol compounds and the use thereof for the synthesis of modified oligonucleotides | ETABLISSEMENT FRANCAIS DU SANG (FR) | 2018-02-20 | — | — | US | disclosed |
| EP-2834253-B1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-03-29 | — | — | EP | disclosed |
| US-20020156311-A1 | Glucocorticoid receptor modulators | KARO BIO AB (SE) | 2002-10-24 | — | — | US | disclosed |
| WO-2002064550-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | ABBOTT LABORATORIES (US) | 2002-08-22 | — | — | WO | disclosed |
| US-5605795-A | Assays using chemiluminescent, enzymatically cleavable substituted 1,2-dioxetanes and kits therefor | TROPIX, INC. (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0716670-A1 | AZO DYES WITH A DIAZO COMPONENT OF THE ANILIN SERIES AND A COUPLING COMPONENT OF THE TRIAZOLOPYRIDINE SERIES | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-19 | — | — | EP | disclosed |
| WO-1995006687-A1 | AZO DYES WITH A DIAZO COMPONENT OF THE ANILIN SERIES AND A COUPLING COMPONENT OF THE TRIAZOLOPYRIDINE SERIES | BASF AKTIENGESELLSCHAFT (DE) | 1995-03-09 | — | — | WO | disclosed |
| US-5220005-A | Reactable with enzyme to release optically detectable energy | TROPIX, INC. (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0037254-B1 | ACETIC ACID DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND COMPOSITION CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1984-07-25 | — | — | EP | disclosed |
| US-4356186-A | ANTIINFLAMMATORY, ANALGESIC, AND ANTIPYRETIC, AGENT | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1982-10-26 | — | — | US | disclosed |
| EP-0037254-A1 | Acetic acid derivatives, process for the preparation thereof and composition containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1981-10-07 | — | — | EP | disclosed |