⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27338867 | 0.97 | HIF1A (0.56) | — | |
| SCHEMBL5174488 | 0.97 | HIF1A (0.56) | — | |
| SCHEMBL3568351 | 0.97 | — | — | |
| SCHEMBL462681 | 0.89 | — | — | |
| SCHEMBL30678314 | 0.84 | — | — | |
| SCHEMBL139711 | 0.84 | — | — | |
| SCHEMBL16816939 | 0.84 | HIF1A (0.82) | — | |
| SCHEMBL30678319 | 0.84 | — | — | |
| SCHEMBL14616447 | 0.81 | HIF1A (0.75) | — | |
| SCHEMBL11356724 | 0.81 | HIF1A (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158573-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2021-08-12 | — | — | WO | claimed |
| WO-2021158573-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2021-08-12 | — | — | WO | disclosed |
| CN-109562085-A | For preventing and treating the diaryl and aryl heteroaryl urea derivative of REM sleep behavior disorder | 阿速万科学有限责任公司 | 2019-04-02 | — | — | CN | disclosed |
| US-20190010144-A1 | SMALL MOLECULE INHIBITOR OF 3-PHOSPHOGLYCERATE DEHYDROGENASE AND USES THEREOF | CORNELL UNIVERSITY | 2019-01-10 | — | — | US | disclosed |
| CN-108472285-A | Diaryl and aryl heteroaryl urea derivatives for the prevention and treatment of hallucinations associated with neurodegenerative diseases | 阿速万科学有限责任公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-7728023-B2 | Indole compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20080188532-A1 | Indole Compound and Use Thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-08-07 | — | — | US | disclosed |
| EP-1852420-A1 | INDOLE COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-11-07 | — | — | EP | disclosed |
| CN-1972944-A | Novel spiroindoline or spiroisoquinoline compounds, methods of use and compositions thereof | ARENA PHARM INC (US) | 2007-05-30 | — | — | CN | disclosed |
| WO-1995020182-A1 | USE OF ARYL OR HETEROARYL AZOANILINES IN NON-LINEAR OPTICS | BASF AKTIENGESELLSCHAFT (DE) | 1995-07-27 | — | — | WO | disclosed |