Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 12/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558723 | 0.84 | DDR1 (0.39) | DDR1 | |
| SCHEMBL2390743 | 0.73 | BRD4 (0.36) | DDR1CA12CA9 | |
| Hydrochloric Acid SCHEMBL2390612 | 0.72 | BRD4 (0.36) | DDR1CA12CA9 | |
| SCHEMBL2389228 | 0.70 | NMT1 (0.41) | DDR1 | |
| SCHEMBL9942859 | 0.67 | PDE3B (0.38) | DDR1CA12CA9 | |
| SCHEMBL2390375 | 0.67 | PTPN5 (0.34) | DDR1CA12CA9 | |
| SCHEMBL1692741 | 0.66 | DDR1 (0.40) | DDR1 | |
| SCHEMBL2391399 | 0.65 | AKR1C3 (0.42) | CA12CA9ALDH1A1 | |
| SCHEMBL2388783 | 0.64 | DDR1 (0.40) | DDR1 | |
| SCHEMBL9942854 | 0.64 | HAVCR2 (0.39) | CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871749-A1 | 1H-QUINAZ0LINE-2,4-DIONES AND THEIR USE AS AMPA-RECEPTOR LIGANDS | Novartis AG (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006108591-A1 | 1H-QUINAZ0LINE-2,4-DIONES AND THEIR USE AS AMPA-RECEPTOR LIGANDS | NOVARTIS AG (CH) | 2006-10-19 | — | — | WO | disclosed |