Phthalic Acid

Phthalic Acid

SCHEMBL4627717

C=CO/C=C/C.C=CO/C=C/C.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
ALOX15 P16050 1/20 0.50
AKR1C3 P42330 2/20 0.41
KDM4E B2RXH2 5/20 0.41
HPGD P15428 5/20 0.41
HSD17B10 Q99714 4/20 0.41
HMGB1 P09429 2/20 0.41
NAPRT Q6XQN6 2/20 0.41
ESR1 P03372 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
TSHR P16473 1/20 0.41
GGT1 P19440 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
BLM P54132 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MYC P01106 2/20 0.40
MAPT P10636 2/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL4605001 0.87 ALDH1A1 (0.56) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL4624401 0.85 ALDH1A1 (0.64) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL20550321 0.85 ALDH1A1 (0.64) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL4605478 0.83 ALDH1A1 (0.61) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Terephthalic Acid SCHEMBL4625730 0.81 TSHR (0.46) ALDH1A1ALOX15HPGDHSD17B10NAPRT
Phthalic Acid SCHEMBL9722583 0.80 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL7192838 0.80 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Isophthalic Acid SCHEMBL4625677 0.79 UNG (0.43) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL28900020 0.78 ALDH1A1 (0.67) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL30776931 0.78 ALDH1A1 (0.74) ALDH1A1ALOX15AKR1C3KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1447217-B1 Heat-sensitive lithographic printing plate FUJIFILM CORP (JP) 2008-06-18 EP disclosed
US-7101649-B2 Heat-sensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2006-09-05 US disclosed
US-20040166431-A1 Heat-sensitive lithographic printing plate FUJIFILM CORPORATION (JP) 2004-08-26 US disclosed
EP-1447217-A2 Heat-sensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2004-08-18 EP disclosed