Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 10/20 | 0.46 |
| ▸ | FPR2 | P25090 | 6/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462837 | 1.00 | FPR1 (0.46) | FPR1FPR2KDM4DAKT1KDM1A | |
| SCHEMBL462836 | 1.00 | FPR1 (0.46) | FPR1FPR2KDM4DAKT1KDM1A | |
| SCHEMBL145666 | 0.89 | FPR1 (0.44) | FPR1FPR2KDM4DKDM1AHTR2C | |
| SCHEMBL5924066 | 0.89 | DPP4 (0.42) | FPR1FPR2KDM1AHTR2CREN | |
| SCHEMBL145667 | 0.89 | FPR1 (0.44) | FPR1FPR2KDM4DKDM1AHTR2C | |
| SCHEMBL145665 | 0.89 | FPR1 (0.44) | FPR1FPR2KDM4DKDM1AHTR2C | |
| SCHEMBL170772 | 0.85 | KDM1A (0.39) | FPR1FPR2AKT1KDM1AEPHX2 | |
| SCHEMBL462830 | 0.85 | KDM1A (0.39) | FPR1FPR2AKT1KDM1AEPHX2 | |
| SCHEMBL148173 | 0.85 | KDM1A (0.39) | FPR1FPR2AKT1KDM1AEPHX2 | |
| SCHEMBL146483 | 0.84 | KDM1A (0.40) | FPR1FPR2KDM4DKDM1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |