Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.70 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4626233 | 0.92 | MAPT (0.68) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL4625682 | 0.91 | MAPT (0.67) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL4626978 | 0.90 | MAPT (0.65) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL4627251 | 0.90 | MAPT (0.65) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL2944261 | 0.89 | MAPT (0.63) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL121636 | 0.88 | MAPT (1.00) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL14340636 | 0.88 | MAPT (0.77) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL11113035 | 0.88 | MAPT (0.77) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL4626845 | 0.87 | MAPT (0.62) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL12830790 | 0.87 | MAPT (0.74) | MAPTPTGDR2PTGDRTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312322-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-12-18 | — | — | US | claimed |
| EP-1888505-A1 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-02-20 | — | — | EP | claimed |
| WO-2006125593-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-11-30 | — | — | WO | claimed |
| US-20080312322-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-12-18 | — | — | US | disclosed |
| EP-1888505-A1 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125593-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312322-A1 | Organic Compounds | NR3C2, MRGPRX2, HRH2 | MAPT 4232/4885PTGDR2 49/4885PTGDR 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.