Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628632 | 0.91 | TSHR (0.43) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL4626630 | 0.91 | TSHR (0.68) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL27816268 | 0.88 | ALDH1A1 (0.56) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL4627220 | 0.87 | TSHR (0.56) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL4626823 | 0.87 | TSHR (0.62) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL4627291 | 0.87 | TSHR (0.51) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| SCHEMBL21113714 | 0.86 | TSHR (0.69) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL6904241 | 0.86 | TSHR (0.55) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL4627303 | 0.86 | TSHR (0.55) | TSHRL3MBTL1TDP1MAPK1CYP3A4 | |
| SCHEMBL4627202 | 0.86 | TSHR (0.55) | TSHRL3MBTL1TDP1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209172-B1 | SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION | TOHO TITANIUM CO LTD (JP) | 2008-07-02 | — | — | EP | disclosed |
| US-6770586-B2 | Solid catalyst component and catalyst for olefins polymerization | TOHO TITANIUM CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| US-20030130109-A1 | Solid catalyst component and catalyst for olefins polymerization | TOHO TITANIUM CO., LTD (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1209172-A1 | SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION | Toho Titanium Co., Ltd. (JP) | 2002-05-29 | — | — | EP | disclosed |