SCHEMBL4628593

SCHEMBL4628593

CCCCCCCCCCCCCCCCCCSc1ccc([O])c(C)c1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 8/20 0.48
CNR2 P34972 2/20 0.43
THRA P10827 1/20 0.43
GPR84 Q9NQS5 3/20 0.43
PLK1 P53350 3/20 0.41
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PTGS2 P35354 2/20 0.39
AR P10275 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3466997 1.00 THRB (0.48) THRBCNR2THRAGPR84PLK1
SCHEMBL200877 0.81 THRB (0.55) THRBTHRAGPR84GAAHTT
SCHEMBL199805 0.81 THRB (0.55) THRBTHRAGPR84GAAHTT
SCHEMBL4628805 0.81 THRB (0.45) THRBCNR2THRAGPR84PLK1
SCHEMBL30726457 0.80 ESR1 (0.49) THRBTHRAPLK1AR
SCHEMBL22075892 0.80 ESR1 (0.49) THRBTHRAPLK1AR
SCHEMBL22075713 0.80 ESR1 (0.49) THRBTHRAPLK1AR
SCHEMBL22075766 0.80 ESR1 (0.49) THRBTHRAPLK1AR
SCHEMBL30726472 0.80 ESR1 (0.49) THRBTHRAPLK1AR
SCHEMBL9140756 0.80 ESR1 (0.49) THRBTHRAPLK1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1917311-A2 MULTIPLE CHROMOPHORES BASF SE (DE) 2008-05-07 EP disclosed
WO-2007014902-A2 MULTIPLE CHROMOPHORES BASED ON RYLENE BASF SE (DE) 2007-02-08 WO disclosed