Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991651 | 1.00 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4L3MBTL1CHRM5 | |
| SCHEMBL812418 | 0.98 | CHRNB2 (0.37) | CHRNB2CHRNA7CHRNA4L3MBTL1CHRM5 | |
| SCHEMBL953414 | 0.98 | CHRNB2 (0.37) | CHRNB2CHRNA7CHRNA4L3MBTL1CHRM5 | |
| SCHEMBL2994601 | 0.98 | CHRNB2 (0.37) | CHRNB2CHRNA7CHRNA4L3MBTL1CHRM5 | |
| SCHEMBL2996449 | 0.96 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4L3MBTL1CHRM5 | |
| SCHEMBL2998727 | 0.96 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4L3MBTL1CHRM5 | |
| SCHEMBL2996446 | 0.96 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4L3MBTL1CHRM5 | |
| SCHEMBL2998728 | 0.96 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4L3MBTL1CHRM5 | |
| SCHEMBL943172 | 0.92 | MEN1 (0.39) | CHRNB2CHRNA7CHRNA4L3MBTL1PARP1 | |
| Proline SCHEMBL28261914 | 0.84 | GRIN2D (0.35) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907378-A1 | PREPARATION OF TERAZOLE DERIVATIVES | Novartis AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007009716-A1 | PREPARATION OF TERAZOLE DERIVATIVES | NOVARTIS AG (CH) | 2007-01-25 | — | — | WO | disclosed |