SCHEMBL4628797

SCHEMBL4628797

CCCCCCCCCCCCCCCCCCN1c2ccccc2C(C)(C)C12C=Nc1c(ccc3ccccc13)O2

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.69
THRB P10828 5/20 0.69
KDM4E B2RXH2 5/20 0.69
SMN1; SMN2 Q16637 4/20 0.69
ALOX12 P18054 2/20 0.69
L3MBTL1 Q9Y468 2/20 0.69
PKM P14618 2/20 0.69
LMNA P02545 4/20 0.54
GAA P10253 4/20 0.54
RECQL P46063 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
ALDH1A1 P00352 2/20 0.54
HPGD P15428 2/20 0.54
HTT P42858 2/20 0.54
MAPK1 P28482 2/20 0.54
POLB P06746 1/20 0.54
NPSR1 Q6W5P4 3/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16315811 0.99 MAPT (0.70) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL14427990 0.96 MAPT (0.72) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL16312948 0.90 MAPT (0.69) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL14552824 0.90 MAPT (0.69) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL8907744 0.90 MAPT (0.56) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL8909435 0.90 MAPT (0.56) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL8908000 0.90 MAPT (0.56) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL8908836 0.90 MAPT (0.56) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL9867221 0.90 MAPT (0.56) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL8909553 0.90 MAPT (0.56) MAPTTHRBKDM4ESMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7425406-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2008-09-16 US disclosed
EP-1621338-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2008-05-07 EP disclosed
US-20060024612-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2006-02-02 US disclosed
EP-1621338-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. (JP) 2006-02-01 EP disclosed
US-5446151-A Photo reactive spiro-benzoxazine compounds PILKINGTON PLC (GB) 1995-08-29 US disclosed
EP-0600669-A1 Photo reactive material PILKINGTON PLC (GB) 1994-06-08 EP disclosed