Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.49 |
| ▸ | DRD3 | P35462 | 9/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201887 | 1.00 | KCNH2 (0.49) | KCNH2DRD3DRD2 | |
| SCHEMBL8247741 | 1.00 | KCNH2 (0.49) | KCNH2DRD3DRD2 | |
| SCHEMBL29914568 | 0.92 | KCNH2 (0.46) | KCNH2DRD3DRD2 | |
| SCHEMBL13823162 | 0.86 | KCNH2 (0.49) | KCNH2DRD3DRD2 | |
| SCHEMBL11911756 | 0.86 | KCNH2 (0.52) | KCNH2DRD3DRD2 | |
| SCHEMBL12313185 | 0.86 | KCNH2 (0.52) | KCNH2DRD3DRD2 | |
| SCHEMBL3397256 | 0.86 | KCNH2 (0.52) | KCNH2DRD3DRD2 | |
| SCHEMBL3769912 | 0.86 | KCNH2 (0.52) | KCNH2DRD3DRD2 | |
| SCHEMBL11915231 | 0.86 | KCNH2 (0.52) | KCNH2DRD3DRD2 | |
| SCHEMBL3769913 | 0.86 | KCNH2 (0.52) | KCNH2DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917242-A1 | AZABICYCLO [3.1.0]HEXYLPHENYL DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022935-A1 | AZABICYCLO [3.1.0] HEXYLPHENYL DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |