Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 5/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26004833 | 0.83 | PNMT (0.64) | PNMTTAAR1IDO1IGF1RALOX15 | |
| SCHEMBL10599873 | 0.81 | PNMT (0.68) | PNMTTAAR1IDO1DPP4DPP7 | |
| SCHEMBL8893657 | 0.81 | PNMT (0.68) | PNMTTAAR1IDO1DPP4DPP7 | |
| SCHEMBL10603412 | 0.80 | PNMT (0.57) | PNMTTAAR1IDO1IGF1RALOX15 | |
| SCHEMBL7258418 | 0.80 | PNMT (0.61) | PNMTTAAR1IDO1DPP4DPP7 | |
| SCHEMBL5706584 | 0.80 | PNMT (0.61) | PNMTTAAR1IDO1DPP4DPP7 | |
| SCHEMBL5706583 | 0.80 | PNMT (0.61) | PNMTTAAR1IDO1DPP4DPP7 | |
| SCHEMBL3058413 | 0.79 | PNMT (1.00) | PNMTTAAR1 | |
| SCHEMBL17413477 | 0.79 | PNMT (1.00) | PNMTTAAR1 | |
| SCHEMBL2424621 | 0.79 | PNMT (0.66) | PNMTTAAR1IDO1IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917006-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT Patent & Licence Trading Ltd. (GB) | 2008-05-07 | — | — | EP | claimed |
| WO-2006136454-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD. (GB) | 2006-12-28 | — | — | WO | claimed |