Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 19/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | HTR1B | P28222 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | FPR3 | P25089 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628260 | 0.84 | ADRB2 (0.73) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL668163 | 0.84 | ADRB2 (0.81) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL939190 | 0.84 | ADRB2 (0.81) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| Acetic Acid SCHEMBL4629147 | 0.81 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL4629384 | 0.78 | ADRB2 (0.63) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL10760810 | 0.78 | ADRB2 (0.62) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5126858 | 0.76 | ADRB2 (0.71) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL10762117 | 0.75 | ADRB2 (0.55) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL10763007 | 0.75 | ADRB2 (0.52) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL5118990 | 0.74 | ADRB2 (0.70) | ADRB2ADRB1ADRB3CYP3A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556342-B1 | PHENETHANOLAMINE DERIVATIVE FOR THE TREATMENT OF RESPIRATORY DISEASES | GLAXO GROUP LTD (GB) | 2008-03-26 | — | — | EP | claimed |