Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899494 | 0.86 | CYP2C19 (0.56) | CYP2C19SMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL31316702 | 0.85 | CYP1A2 (0.59) | CYP2C19SMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL29952474 | 0.85 | KMT2A (0.49) | SMN1; SMN2KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL29956325 | 0.85 | KMT2A (0.49) | SMN1; SMN2KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL13839686 | 0.84 | SMN1; SMN2 (0.50) | CYP2C19SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL13841303 | 0.84 | SMN1; SMN2 (0.50) | CYP2C19SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL13839703 | 0.84 | SMN1; SMN2 (0.50) | CYP2C19SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL4629345 | 0.84 | POLB (0.43) | SMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL4630091 | 0.84 | SMN1; SMN2 (0.41) | CYP2C19SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21009509 | 0.84 | ATM (0.51) | KDM4EHSD17B10L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694630-B1 | METHOD FOR PRODUCING CHIRAL OR ENANTIOMER-ENRICHED BETA-AMINO ACIDS, -ALDEHYDES, -KETONES AND GAMMA-AMINO ALCOHOLS | DSM FINE CHEM AUSTRIA GMBH (AT) | 2008-05-07 | — | — | EP | disclosed |
| US-20070123589-A1 | Method for producing chiral or enantiomer-enriched beta-amino acids, aldehydes, ketones and gama-amino alcohols | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2007-05-31 | — | — | US | disclosed |
| EP-1694630-A1 | IMPROVED METHOD FOR PRODUCING CHIRAL OR ENANTIOMER-ENRICHED BETA-AMINO ACIDS, -ALDEHYDES, -KETONES AND GAMMA-AMINO ALCOHOLS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005063682-A1 | IMPROVED METHOD FOR PRODUCING CHIRAL OR ENANTIOMER-ENRICHED BETA-AMINO ACIDS, -ALDEHYDES, -KETONES AND GAMMA-AMINO ALCOHOLS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123589-A1 | Method for producing chiral or enantiomer-enriched beta-amino acids, aldehydes, ketones and gama-amino alcohols | GLRA1, GLRB, GLRA2 | CYP2C19 880/4885SMN1; SMN2 3427/4885KMT2A 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.