Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956325 | 1.00 | KMT2A (0.49) | KMT2ALMNASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL253718 | 0.86 | ALDH1A1 (0.42) | KMT2ALMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL1273278 | 0.86 | ALDH1A1 (0.42) | KMT2ALMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4629199 | 0.85 | CYP2C19 (0.53) | KMT2ALMNASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL708352 | 0.83 | GPR88 (0.45) | KMT2ALMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL4020125 | 0.82 | HDAC4 (0.44) | MAPK1 | |
| SCHEMBL2786917 | 0.81 | KDM4E (0.55) | KMT2ALMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL186416 | 0.80 | LMNA (0.61) | KMT2ALMNASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL8582093 | 0.80 | RIPK1 (0.61) | KMT2ALMNASMN1; SMN2MAPK1 | |
| SCHEMBL186230 | 0.80 | LMNA (0.61) | KMT2ALMNASMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |