Tyrosine

Tyrosine

SCHEMBL4629448

C[C@H](N)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.86
PTGS1 P23219 3/20 0.61
ALPI P09923 1/20 0.61
PKM P14618 1/20 0.61
XIAP P98170 1/20 0.61
TAAR1 Q96RJ0 3/20 0.58
SLC6A2 P23975 1/20 0.58
HIF1A Q16665 3/20 0.57
ALOX15 P16050 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
KDM4E B2RXH2 1/20 0.57
USP2 O75604 1/20 0.57
EGFR P00533 1/20 0.57
LCK P06239 1/20 0.57
FYN P06241 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
HTR2A P28223 1/20 0.57
PTGS2 P35354 1/20 0.57
RECQL P46063 1/20 0.57
HSD17B10 Q99714 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL4301284 1.00 SLC7A5 (0.86) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL9937710 1.00 SLC7A5 (0.86) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL20703797 1.00 SLC7A5 (0.86) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL10804023 1.00 SLC7A5 (0.86) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28049225 0.95 SLC7A5 (0.77) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL2284689 0.95 SLC7A5 (0.77) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28019917 0.95 SLC7A5 (0.77) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1853798 0.94 SLC7A5 (0.75) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL29780694 0.93 SLC7A5 (0.86) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL5222909 0.93 SLC7A5 (0.92) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106478777-A Staphylococcus aureus FnBPA A albumen mimic epitope peptide, mimic epitope peptide combinations and its application with immune protective 安徽农业大学 2017-03-08 CN claimed
US-6440691-B1 AIDS VIRICIDES LARGE SCALE BIOLOGY CORPORATION 2002-08-27 US claimed
US-20020039726-A1 Melanins with improved ability to inhibit HIV replication GARGER STEVEN (US) 2002-04-04 US claimed
US-6300057-B1 TREATING HIV INFECTIONS BY ADMINISTERING A THERAPEUTIC DOSE OF SYNTHESIZED MELANIN CONTAINING AN ANIONIC GROUP OF SULFATES AND SULFONYLS; NONTOXIC THERAPY OF HUMAN IMMUNODEFICIENCY VIRUS LARGE SCALE BIOLOGY CORPORATION 2001-10-09 US claimed
EP-1095652-A2 Melanins with improved ability to inhibit HIV replication Biosource Technologies, Inc. (US) 2001-05-02 EP claimed
EP-1014964-A1 MELANINS WITH IMPROVED ABILITY TO INHIBIT HIV REPLICATION Biosource Technologies, Inc. (US) 2000-07-05 EP claimed
WO-1998034606-A1 MELANINS WITH IMPROVED ABILITY TO INHIBIT HIV REPLICATION BIOSOURCE TECHNOLOGIES, INC. (US) 1998-08-13 WO claimed
US-5576326-A Copper amino acidate diimine nitrate compounds and their methyl derivatives and a process for preparing them UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (UNAM) (MX) 1996-11-19 US claimed
CN-117740961-A Compound analysis method of liquorice and liquorice probiotics fermentation preparation 北京中医药大学 2024-03-22 CN disclosed
CN-115639360-A Preparation of precursor gastrin (PG 80) antibody and establishment of CLIA detection PG80 kit 武汉市朗典精医生物科技有限公司 2023-01-24 CN disclosed
US-20220162656-A1 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES HERCULES CAPITAL, INC., AS AGENT 2022-05-26 US disclosed
CN-114371280-A Plasma biomarker for broiler AFB1 poisoning diagnosis and application thereof 河南农业大学 2022-04-19 CN disclosed
CN-109646439-B Cyclic dipeptide for promoting wound healing and application thereof in pharmacy 四川好医生攀西药业有限责任公司 2021-11-16 CN disclosed
WO-2020085735-A1 METHOD FOR PREPARING BIOCONVERSION PRODUCTS OF ASPARAGUS COCHINCHINENSIS AND SOYBEAN EMBRYOS BY MEANS OF LIQUID CULTURING OF BASIDIOMYCETES MYCELIUM, AND USE THEREOF (주)큐젠바이오텍 2020-04-30 WO disclosed
WO-1998038876-A1 METHOD OF INHIBITING GROWTH OF MICROORGANISMS BY LASER RADIATION MAEKELAE ANU MAARIT (FI) 1998-09-11 WO disclosed
US-5576326-A Copper amino acidate diimine nitrate compounds and their methyl derivatives and a process for preparing them UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (UNAM) (MX) 1996-11-19 US disclosed
US-4727189-A ANALGESICS, ANTIHYPERTENSIVE AGENTS G. D. SEARLE & CO. (US) 1988-02-23 US disclosed
US-4681852-A MUTANT ESCHERICHIA COLI, PHENYLALANINE AUSTGEN-BIOJET INTERNATIONAL PTY, LTD. (AU) 1987-07-21 US disclosed
US-4599325-A ANALGESIC, HYPOTENSIVE G. D. SEARLE & CO. (US) 1986-07-08 US disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed