Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | TOP2A | P11388 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9805908 | 0.85 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL11112093 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL22579210 | 0.82 | KDM4E (0.72) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| Ciprofloxacin SCHEMBL28061283 | 0.81 | KDM4E (0.89) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL9678335 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL28022274 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL10670664 | 0.78 | MEN1 (0.56) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| Ciprofloxacin SCHEMBL28201587 | 0.78 | KDM4E (0.96) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| Ciprofloxacin SCHEMBL4459712 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| Ciprofloxacin SCHEMBL2900 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711468-B1 | PROCESS FOR PREPARING PURIFIED CIPROFLOXACIN | KRKA TOVARNA ZDRAVIL D D NOVO (SI) | 2008-05-14 | — | — | EP | disclosed |
| EP-1711468-A1 | PROCESS FOR PREPARING PURIFIED CIPROFLOXACIN | KRKA, tovarna zdravil, d.d., Novo mesto (SI) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005075430-A1 | PROCESS FOR PREPARING PURIFIED CIPROFLOXACIN | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2005-08-18 | — | — | WO | disclosed |