SCHEMBL4629980

SCHEMBL4629980

C=CC=Cc1cc[c]cc1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.36
APP P05067 2/20 0.32
TRPA1 O75762 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
ALOX5 P09917 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28830693 1.00 MAOB (0.36) MAOBAPPTRPA1ALDH1A1LMNA
SCHEMBL294613 0.91 APP (0.39) MAOBAPP
SCHEMBL294614 0.91 APP (0.39) MAOBAPP
SCHEMBL152100 0.78 MAOB (0.33) MAOBAPPTRPA1ALDH1A1LMNA
SCHEMBL210914 0.78 MAOB (0.33) MAOBAPPTRPA1ALDH1A1LMNA
SCHEMBL787790 0.75 ALDH1A1 (0.58) MAOBAPPTRPA1ALDH1A1LMNA
SCHEMBL93419 0.74 MAOB (0.68) MAOBTRPA1ALDH1A1LMNAALOX5
SCHEMBL4445282 0.74 ALDH1A1 (0.61) MAOBAPPTRPA1ALDH1A1LMNA
SCHEMBL33879 0.74 MAOB (0.68) MAOBTRPA1ALDH1A1LMNAALOX5
SCHEMBL4936136 0.74 MAOB (0.68) MAOBTRPA1ALDH1A1LMNAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109695660-B Glass apron processing shock attenuation platform 江苏摩臣智联科技有限公司 2021-08-06 CN disclosed
CN-102850336-A DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMA CO LTD 2013-01-02 CN disclosed
CN-100490212-C Method and apparatus for manufacturing active-matrix organic EL display, active-matrix organic EL display, method for manufacturing liquid crystal array, liquid crystal array, filter substrate, method SHARP KK KONICA MINOLTA HOLDIN (JP) 2009-05-20 CN disclosed
EP-1919907-A2 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-05-14 EP disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed
CN-1701641-A Method and apparatus for manufacturing active-matrix organic EL display, active-matrix organic EL display, method for manufacturing liquid crystal array, liquid crystal array, method and apparatus for SHARP KK (JP) 2005-11-23 CN disclosed
US-6420409-B1 GLUCOSE TOLERANCE, DIABETES,INSULIN RESISTANCE, POLYCYSTIC OVARY SYNDROME, HYPERLIPIDEMIA, ATHEROSCLEROSIS, CARDIOVASCULAR DISORDERS, HYPERGLYCEMIA, HYPERTENSION, STENOCARDIA, PULMONARY HYPERTENSION, CONGESTIVE HEART FAILURE, FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-07-16 US disclosed
EP-1020452-A1 BENZIMIDAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-19 EP disclosed