Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294467 | 0.80 | — | — | |
| SCHEMBL3869954 | 0.71 | HRH3 (0.41) | HRH3 | |
| SCHEMBL28237829 | 0.71 | HRH3 (0.41) | HRH3 | |
| SCHEMBL734711 | 0.71 | — | — | |
| SCHEMBL24114952 | 0.70 | HRH3 (0.44) | HRH3 | |
| SCHEMBL4556064 | 0.70 | HRH3 (0.44) | HRH3 | |
| Water SCHEMBL22609081 | 0.70 | HRH3 (0.40) | HRH3 | |
| Water SCHEMBL28467825 | 0.68 | HRH3 (0.42) | HRH3 | |
| SCHEMBL2099498 | 0.68 | CYP1A2 (0.34) | — | |
| SCHEMBL6506199 | 0.67 | L3MBTL1 (0.33) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |