Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463038 | 1.00 | GPR119 (0.50) | GPR119GPR183KCNH2ACACBMET | |
| SCHEMBL463157 | 0.81 | GPR119 (0.31) | GPR119GPR183KCNH2 | |
| SCHEMBL463156 | 0.81 | GPR119 (0.31) | GPR119GPR183KCNH2 | |
| SCHEMBL463158 | 0.81 | GPR119 (0.31) | GPR119GPR183KCNH2 | |
| SCHEMBL470604 | 0.81 | GPR119 (0.49) | GPR119GPR183KCNH2 | |
| SCHEMBL463039 | 0.79 | GPR119 (0.32) | GPR119KCNH2MET | |
| SCHEMBL470700 | 0.78 | GPR119 (0.53) | GPR119GPR183KCNH2ACACB | |
| SCHEMBL470632 | 0.78 | GPR119 (0.58) | GPR119GPR183KCNH2ACACB | |
| SCHEMBL470613 | 0.78 | GPR119 (0.49) | GPR119GPR183KCNH2 | |
| SCHEMBL470648 | 0.77 | GPR119 (0.49) | GPR119GPR183KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |