Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322592 | 0.93 | — | — | |
| SCHEMBL8561684 | 0.84 | — | — | |
| SCHEMBL2531258 | 0.82 | NAAA (0.56) | NAAATSHREPHX1CA12CA1 | |
| SCHEMBL2945479 | 0.80 | NAAA (0.59) | NAAATSHREPHX1CA12CA1 | |
| SCHEMBL2529455 | 0.80 | NAAA (0.59) | NAAATSHREPHX1CA12CA1 | |
| SCHEMBL2940576 | 0.80 | NAAA (0.59) | NAAATSHREPHX1CA12CA1 | |
| SCHEMBL2530487 | 0.80 | NAAA (0.59) | NAAATSHREPHX1CA12CA1 | |
| SCHEMBL2946409 | 0.80 | NAAA (0.59) | NAAATSHREPHX1CA12CA1 | |
| SCHEMBL2530636 | 0.80 | NAAA (0.59) | NAAATSHREPHX1CA12CA1 | |
| SCHEMBL2529555 | 0.80 | NAAA (0.59) | NAAATSHREPHX1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| US-4762839-A | Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications | TANABE SEIYAKU CO., LTD. (JP) | 1988-08-09 | — | — | US | disclosed |
| EP-0204534-A2 | Quinazolinone compounds and processes for the preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1986-12-10 | — | — | EP | disclosed |