Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 11/20 | 0.65 |
| ▸ | HTR1B | P28222 | 10/20 | 0.65 |
| ▸ | HTR2C | P28335 | 6/20 | 0.54 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 4/20 | 0.52 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.52 |
| ▸ | HTR3B | O95264 | 2/20 | 0.52 |
| ▸ | HTR1E | P28566 | 2/20 | 0.52 |
| ▸ | HTR1F | P30939 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | HTR5A | P47898 | 2/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686111 | 0.79 | HTR1D (1.00) | HTR1DHTR1BHTR2CHTR1AHTR2A | |
| SCHEMBL8475951 | 0.79 | HTR1D (0.61) | HTR1DHTR1BHTR2CHTR1AHTR2A | |
| SCHEMBL8688690 | 0.78 | HTR1D (1.00) | HTR1DHTR1BHTR2CHTR1AHTR2A | |
| SCHEMBL7331855 | 0.78 | HTR1D (0.60) | HTR1DHTR1BHTR2CHTR1AHTR2A | |
| SCHEMBL9094694 | 0.77 | HTR1D (0.58) | HTR1DHTR1BHTR2CHTR1AHTR2A | |
| SCHEMBL9096990 | 0.77 | HTR1D (0.56) | HTR1DHTR1BHTR2CHTR1AHTR2A | |
| SCHEMBL9094771 | 0.76 | HTR1D (0.57) | HTR1DHTR1BHTR2CHTR1AHTR2A | |
| SCHEMBL7323553 | 0.76 | HTR1D (0.68) | HTR1DHTR1BHTR2CHTR1AHTR2A | |
| SCHEMBL7324823 | 0.76 | HTR1D (0.68) | HTR1DHTR1BHTR2CHTR1AHTR2A | |
| SCHEMBL8686553 | 0.76 | HTR1D (1.00) | HTR1DHTR1BHTR2CHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132463-B1 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI AVENTIS (FR) | 2008-10-29 | — | — | EP | disclosed |
| EP-0838217-B1 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI SYNTHELABO (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1132463-A2 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| US-6114336-A | Cosmetic composition containing a neuropeptide Y receptor antagonist | SANOFI (FR) | 2000-09-05 | — | — | US | disclosed |
| US-5827853-A | MIXTURE CONTAINING PRODUCT FROM FERMENTATION BY STREPTOMYCES FOR TOPICAL APPLICATION TO SKIN OR HAIR, TO IMPROVE TEXTURE, SURFACE SMOOTHNESS, FIRMNESS | SANOFI (FR) | 1998-10-27 | — | — | US | disclosed |
| EP-0838217-A2 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |
| EP-0571471-B1 | 5-HETEROYL INDOLE DERIVATIVES | PFIZER (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5409941-A | 5-heteroyl indole derivatives | PFIZER INC. (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1992013856-A1 | 5-HETEROYL INDOLE DERIVATIVES | PFIZER INC. (US) | 1992-08-20 | — | — | WO | disclosed |