Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 12/20 | 0.68 |
| ▸ | HTR1B | P28222 | 10/20 | 0.68 |
| ▸ | HTR1A | P08908 | 5/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.63 |
| ▸ | HTR2C | P28335 | 4/20 | 0.63 |
| ▸ | MPO | P05164 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 3/20 | 0.60 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | HTR5A | P47898 | 3/20 | 0.60 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.60 |
| ▸ | HTR3B | O95264 | 2/20 | 0.60 |
| ▸ | HTR1E | P28566 | 2/20 | 0.60 |
| ▸ | HTR1F | P30939 | 2/20 | 0.60 |
| ▸ | HTR3A | P46098 | 2/20 | 0.60 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.60 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.60 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323553 | 0.89 | HTR1D (0.68) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL29633081 | 0.88 | HTR1A (0.70) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL4055413 | 0.88 | HTR1A (0.70) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL7324098 | 0.87 | MPO (0.79) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL7328883 | 0.87 | HTR1D (0.67) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL7332860 | 0.85 | HTR1D (0.80) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL7331468 | 0.84 | HTR1D (0.66) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL7325323 | 0.82 | HTR2A (0.77) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL7327470 | 0.82 | HTR1D (0.62) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL8869593 | 0.82 | HTR1D (0.71) | HTR1DHTR1BHTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |