Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216712 | 0.91 | ESR1 (0.58) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL31274990 | 0.91 | ESR1 (0.58) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL40254 | 0.91 | ESR1 (0.58) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL133408 | 0.91 | ESR1 (0.58) | ESR1ESR2PDCD1CD274ALOX15 | |
| Methane SCHEMBL7206625 | 0.88 | ESR1 (0.55) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL10445993 | 0.82 | ESR1 (0.65) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL982047 | 0.80 | IDO1 (0.56) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL17995329 | 0.80 | IDO1 (0.56) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL19314626 | 0.80 | IDO1 (0.56) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL22694327 | 0.80 | IDO1 (0.56) | ESR1ESR2PDCD1CD274ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1475398-B1 | INDOLE RESINS, EPOXY RESINS AND RESIN COMPOSITIONS CONTAINING THE SAME | NIPPON STEEL CHEMICAL CO (JP) | 2008-05-14 | — | — | EP | disclosed |
| EP-1475398-A1 | INDOLE RESINS, EPOXY RESINS AND RESIN COMPOSITIONS CONTAINING THE SAME | Nippon Steel Chemical Co., Ltd. (JP) | 2004-11-10 | — | — | EP | disclosed |