Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630840 | 1.00 | MAPT (0.64) | MAPTALDH1A1HCAR2ATMFAAH | |
| SCHEMBL2618106 | 0.93 | MAPT (0.72) | MAPTALDH1A1HCAR2ATMFAAH | |
| SCHEMBL1885350 | 0.93 | MAPT (0.72) | MAPTALDH1A1HCAR2ATMFAAH | |
| SCHEMBL264932 | 0.91 | HCAR2 (0.50) | MAPTALDH1A1HCAR2ATMKEAP1 | |
| SCHEMBL1879680 | 0.91 | HCAR2 (0.50) | MAPTALDH1A1HCAR2ATMKEAP1 | |
| SCHEMBL9527552 | 0.91 | HCAR2 (0.50) | MAPTALDH1A1HCAR2ATMKEAP1 | |
| Phosphoric Acid SCHEMBL3668643 | 0.87 | MAPT (0.66) | MAPTALDH1A1HCAR2ATMFAAH | |
| Phosphoric Acid SCHEMBL3668645 | 0.87 | MAPT (0.66) | MAPTALDH1A1HCAR2ATMFAAH | |
| SCHEMBL872986 | 0.87 | MAPT (0.70) | MAPTALDH1A1HCAR2ATMFAAH | |
| SCHEMBL872985 | 0.87 | MAPT (0.70) | MAPTALDH1A1HCAR2ATMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080247966-A1 | Compositions and Methods to Counteract Oral Malodour | GIVAUDAN SA (CH) | 2008-10-09 | — | — | US | disclosed |
| EP-1919566-A1 | COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR | Givaudan SA (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007025401-A1 | COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR | GIVAUDAN SA (CH) | 2007-03-08 | — | — | WO | disclosed |