SCHEMBL264932

SCHEMBL264932

CCCC/C=C/C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.50
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
MAPT P10636 1/20 0.48
F7 P08709 1/20 0.44
F3 P13726 1/20 0.44
ATM Q13315 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
PPARG P37231 2/20 0.42
PPARA Q07869 2/20 0.42
EPHX2 P34913 1/20 0.40
ALOX5 P09917 1/20 0.40
OXER1 Q8TDS5 1/20 0.40
PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1879680 1.00 HCAR2 (0.50) HCAR2KEAP1NFE2L2MAPTF7
SCHEMBL9527552 1.00 HCAR2 (0.50) HCAR2KEAP1NFE2L2MAPTF7
SCHEMBL11874320 0.96 KEAP1 (0.46) HCAR2KEAP1NFE2L2MAPTF7
SCHEMBL11874324 0.96 KEAP1 (0.46) HCAR2KEAP1NFE2L2MAPTF7
SCHEMBL1404268 0.94 CNR1 (0.49) HCAR2KEAP1NFE2L2MAPTF7
SCHEMBL1404267 0.94 CNR1 (0.49) HCAR2KEAP1NFE2L2MAPTF7
SCHEMBL11743976 0.92 PPARG (0.51) MAPTF7F3ATMCNR1
SCHEMBL347470 0.92 PPARG (0.51) MAPTF7F3ATMCNR1
SCHEMBL22555434 0.92 PPARG (0.51) MAPTF7F3ATMCNR1
SCHEMBL14672999 0.92 PPARG (0.51) MAPTF7F3ATMCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003467-A Novel triphosphine compound and synthetic method and application thereof 惠州凯特立斯科技有限公司 2023-04-25 CN claimed
CN-115772195-A Pyridine-based phosphine ligand compound and application thereof 惠州凯特立斯科技有限公司 2023-03-10 CN claimed
CN-114957327-A Synthesis method of benzene-based tetraphosphine ligand 惠州凯特立斯科技有限公司 2022-08-30 CN claimed
CN-114835746-A Novel tetradentate phosphine ligand compound and synthetic method and application thereof 惠州凯特立斯科技有限公司 2022-08-02 CN claimed
CN-114805434-A Novel tetradentate phosphine ligand compound and synthetic method and application thereof 惠州凯特立斯科技有限公司 2022-07-29 CN claimed
US-20080311054-A1 Compositions and Methods to Counteract Oral Malodour GIVAUDAN SA (CH) 2008-12-18 US claimed
US-20080247966-A1 Compositions and Methods to Counteract Oral Malodour GIVAUDAN SA (CH) 2008-10-09 US claimed
EP-1937365-A1 COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR Givaudan SA (CH) 2008-07-02 EP claimed
EP-1919566-A1 COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR Givaudan SA (CH) 2008-05-14 EP claimed
WO-2007025401-A1 COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR GIVAUDAN SA (CH) 2007-03-08 WO claimed
WO-2007025402-A1 COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR GIVAUDAN SA (CH) 2007-03-08 WO claimed
JP-1305051-A None JP disclosed
CN-116640072-B Method for synthesizing oxime compound by catalyzing hydrocarbon bond oxidation through tetradentate nitrogen-containing coordination manganese 陕西师范大学 2025-02-28 CN disclosed
WO-2023178197-A1 RECOMBINANT MICROBES FOR PRODUCTION OF TRANS-2 UNSATURATED FATTY ACIDS AND DERIVATIVES THEREOF GENOMATICA, INC. (US) 2023-09-21 WO disclosed
CN-116640072-A Method for synthesizing oxime compound by catalyzing hydrocarbon bond oxidation through tetradentate nitrogen-containing coordination manganese 陕西师范大学 2023-08-25 CN disclosed
WO-1995014683-A1 NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-06-01 WO disclosed
JP-H01305051-A PRODUCTION OF OMEGA ENECARBOXYLIC ESTER HUELS AG 1989-12-08 JP disclosed
EP-0334455-A1 Process for the production of keto-diesters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-09-27 EP disclosed
US-4800231-A Keto-diesters production SHELL OIL COMPANY (US) 1989-01-24 US disclosed
US-4052423-A FROM A VINYLMERCURIC HALIDE, CARBON MONOXIDE AND ALCOHOL IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311054-A1 Compositions and Methods to Counteract Oral Malodour TAS2R60, TAS2R40, LPO HCAR2 1404/4885KEAP1 406/4885NFE2L2 537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.