SCHEMBL4630894

SCHEMBL4630894

CCOC(=O)c1cc(N)ccc1-c1c2ccc(=O)cc-2oc2cc(OCC(=O)OC(C)(C)C)ccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 5/20 0.44
ABCB1 P08183 1/20 0.43
ALDH1A1 P00352 6/20 0.43
HPGD P15428 6/20 0.43
MAPT P10636 4/20 0.43
GAA P10253 3/20 0.43
HSD17B10 Q99714 3/20 0.43
GLA P06280 2/20 0.43
TP53 P04637 1/20 0.43
MAPK1 P28482 1/20 0.43
CFTR P13569 1/20 0.42
PAX8 Q06710 1/20 0.42
ATM Q13315 1/20 0.42
GOPC Q9HD26 1/20 0.42
LMNA P02545 2/20 0.39
POLB P06746 3/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4630565 0.95 USP2 (0.47) USP2L3MBTL1KDM4EABCB1ALDH1A1
SCHEMBL4630010 0.88 CA9 (0.42) USP2L3MBTL1KDM4EALDH1A1HPGD
SCHEMBL4630755 0.84 MAPT (0.42) KDM4EALDH1A1HPGDMAPTGAA
SCHEMBL4631325 0.84 KDM4E (0.41) KDM4EALDH1A1HPGDMAPTGAA
SCHEMBL2464428 0.82 USP2 (0.73) USP2L3MBTL1ABCB1ALDH1A1CFTR
SCHEMBL14008335 0.81 KDM4E (0.51) USP2L3MBTL1KDM4EABCB1ALDH1A1
SCHEMBL4631742 0.81 MAPT (0.42) KDM4EALDH1A1HPGDMAPTGAA
SCHEMBL14035116 0.81 KDM4E (0.50) USP2L3MBTL1KDM4EABCB1ALDH1A1
SCHEMBL14008329 0.79 KDM4E (0.50) USP2L3MBTL1KDM4EABCB1ALDH1A1
SCHEMBL14008331 0.79 KDM4E (0.48) USP2L3MBTL1KDM4EABCB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080275215-A1 Fluorescein-Based Compounds And Their Use For Peptide Synthesis COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-11-06 US disclosed
EP-1749870-B1 Fluorescein-based compounds and their use for peptide synthesis COMMISSARIAT ENERGIE ATOMIQUE (FR) 2008-05-14 EP disclosed
EP-1749870-A1 Fluorescein-based compounds and their use for peptide synthesis COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2007-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275215-A1 Fluorescein-Based Compounds And Their Use For Peptide Synthesis DNPEP, ANPEP, PEPD USP2 1795/4885L3MBTL1 3821/4885KDM4E 4808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.