Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | PLEC | Q15149 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 9/20 | 0.47 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882008 | 0.93 | USP2 (0.66) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL4631151 | 0.93 | USP2 (0.66) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL15496802 | 0.89 | USP2 (0.77) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL17920161 | 0.88 | USP2 (0.78) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL30023431 | 0.84 | USP2 (1.00) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL3481432 | 0.84 | USP2 (1.00) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL4630894 | 0.82 | USP2 (0.50) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL23084928 | 0.81 | USP2 (0.71) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL14646715 | 0.81 | USP2 (0.61) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL13384808 | 0.79 | USP2 (0.85) | USP2L3MBTL1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190022100-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY INC (US) | 2019-01-24 | — | — | US | disclosed |
| US-10098887-B2 | Antiviral compounds and methods of use thereof | TRANA DISCOVERY, INC. (US) | 2018-10-16 | — | — | US | disclosed |
| US-20160129006-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY INC (US) | 2016-05-12 | — | — | US | disclosed |
| US-9173886-B2 | Antiviral compounds and methods of use thereof | TRANA DISCOVERY, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20130071353-A1 | Antiviral Compounds and Methods of Use Thereof | TRANA DISCOVERY, INC (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2011113060-A2 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY, INC. (US) | 2011-09-15 | — | — | WO | disclosed |
| US-20080275215-A1 | Fluorescein-Based Compounds And Their Use For Peptide Synthesis | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-11-06 | — | — | US | disclosed |
| EP-1749870-B1 | Fluorescein-based compounds and their use for peptide synthesis | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2008-05-14 | — | — | EP | disclosed |
| EP-1749870-A1 | Fluorescein-based compounds and their use for peptide synthesis | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2007-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275215-A1 | Fluorescein-Based Compounds And Their Use For Peptide Synthesis | DNPEP, ANPEP, PEPD | USP2 1795/4885L3MBTL1 3821/4885MEN1 2416/4885 |
| US-10098887-B2 | Antiviral compounds and methods of use thereof | TYMP, MAVS, ZC3HAV1 | USP2 3599/4885L3MBTL1 528/4885MEN1 4495/4885 |
| US-20160129006-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TYMP, MAVS, ZC3HAV1 | USP2 3599/4885L3MBTL1 528/4885MEN1 4495/4885 |
| US-20130071353-A1 | Antiviral Compounds and Methods of Use Thereof | TYMP, MAVS, ZC3HAV1 | USP2 3599/4885L3MBTL1 528/4885MEN1 4495/4885 |
| US-20190022100-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TYMP, MAVS, ZC3HAV1 | USP2 3599/4885L3MBTL1 528/4885MEN1 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.