Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630078 | 0.85 | NOTUM (0.47) | NOTUMMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4496878 | 0.78 | NOTUM (0.55) | NOTUMMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4629920 | 0.78 | NOTUM (0.44) | NOTUMMAPK1L3MBTL1KMT2ATSHR | |
| SCHEMBL6206132 | 0.78 | NOTUM (0.44) | NOTUMMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4709914 | 0.78 | NOTUM (0.44) | NOTUMMAPK1L3MBTL1KMT2ATSHR | |
| SCHEMBL28226817 | 0.76 | KMT2A (0.49) | NOTUMMAPK1L3MBTL1KMT2ATSHR | |
| SCHEMBL31033005 | 0.76 | KMT2A (0.49) | NOTUMMAPK1L3MBTL1KMT2ATSHR | |
| SCHEMBL4102887 | 0.76 | NOTUM (0.47) | NOTUMMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6470773 | 0.76 | NOTUM (0.43) | NOTUMMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28878881 | 0.75 | LMNA (0.47) | NOTUMMAPK1L3MBTL1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799797-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-05-14 | — | — | EP | claimed |