Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261784 | 0.67 | — | — | |
| SCHEMBL8693124 | 0.64 | — | — | |
| SCHEMBL6267384 | 0.62 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL3676079 | 0.62 | — | — | |
| SCHEMBL17827137 | 0.61 | — | — | |
| SCHEMBL1627758 | 0.61 | — | — | |
| SCHEMBL7605633 | 0.59 | TSHR (0.48) | ABAT | |
| SCHEMBL11742511 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL28121176 | 0.59 | — | — | |
| Carbamic Acid SCHEMBL9694988 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614049-A1 | PLEUROMUTILIN DERIVATIVES FOR USE IN THE TREATMENT OF DISEASES MEDIATED BY MICROBES | Nabriva Therapeutics AG (AT) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012031307-A1 | PLEUROMUTILIN DERIVATIVES FOR USE IN THE TREATMENT OF DISEASES MEDIATED BY MICROBES | NABRIVA THERAPEUTICS AG (AT) | 2012-03-15 | — | — | WO | disclosed |