SCHEMBL4631552

SCHEMBL4631552

CN(C)c1ccc(C(O)(/C=C/c2ccccc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.61
RAB9A P51151 4/20 0.51
NPC1 O15118 3/20 0.51
MAPT P10636 2/20 0.51
KMT2A Q03164 2/20 0.51
CASP3 P42574 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CYP1B1 Q16678 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
SLC2A1 P11166 1/20 0.50
KDM4E B2RXH2 2/20 0.47
APP P05067 6/20 0.46
HSD17B3 P37058 1/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631554 1.00 RELA (0.61) RELARAB9ANPC1MAPTKMT2A
SCHEMBL9448703 0.95 RELA (0.59) RELARAB9ANPC1MAPTKMT2A
SCHEMBL9448701 0.95 RELA (0.59) RELARAB9ANPC1MAPTKMT2A
SCHEMBL4630824 0.83 KDM4E (0.48) RAB9ANPC1MAPTSMN1; SMN2CYP1B1
SCHEMBL4630827 0.83 KDM4E (0.48) RAB9ANPC1MAPTSMN1; SMN2CYP1B1
SCHEMBL9349657 0.78 RELA (0.54) RELARAB9ANPC1MAPTKMT2A
SCHEMBL9448711 0.78 RELA (0.54) RELARAB9ANPC1MAPTKMT2A
SCHEMBL9448714 0.78 RELA (0.54) RELARAB9ANPC1MAPTKMT2A
SCHEMBL1557244 0.77 RELA (1.00) RELARAB9ANPC1MAPTKMT2A
SCHEMBL1557242 0.77 RELA (1.00) RELARAB9ANPC1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed