SCHEMBL4631940

SCHEMBL4631940

CC(=Cc1ccc(N)cc1)CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.40
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
GFER P55789 1/20 0.38
CYP19A1 P11511 6/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
TRPA1 O75762 2/20 0.33
ACHE P22303 1/20 0.33
NQO2 P16083 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CA3 P07451 1/20 0.33
CYP3A4 P08684 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631936 1.00 APP (0.40) APPNPC1RAB9AGFERCYP19A1
SCHEMBL18483455 0.83 CYP19A1 (0.41) APPNPC1RAB9AGFERCYP19A1
SCHEMBL1758165 0.80 CYP2A6 (0.41) NPC1RAB9AMAPTKMT2AACHE
SCHEMBL1758330 0.80 CYP2A6 (0.41) NPC1RAB9AMAPTKMT2AACHE
SCHEMBL3589921 0.79 TYR (0.47) NPC1RAB9AMAPTTRPA1ALDH1A1
SCHEMBL3589919 0.79 TYR (0.47) NPC1RAB9AMAPTTRPA1ALDH1A1
SCHEMBL6366611 0.78 CAPN1 (0.42) APPTRPA1NQO2ALDH1A1ALOX15
SCHEMBL4632154 0.78 TRPA1 (0.50) TRPA1ALDH1A1HSD17B10GRIK1
SCHEMBL3602795 0.78 TRPA1 (0.55) MEN1MAPTKMT2ATRPA1
SCHEMBL3600589 0.78 KMT2A (0.44) NPC1RAB9ACYP19A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed