SCHEMBL4631985

SCHEMBL4631985

O=[N+]([O-])c1ccc(/C=C(\Br)CO)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 3/20 0.54
APP P05067 1/20 0.47
MAPT P10636 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 1/20 0.46
PTGS2 P35354 3/20 0.45
PTGS1 P23219 1/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
GSK3B P49841 1/20 0.43
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2B Q13224 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
BRAF P15056 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631989 1.00 FBP1 (0.54) FBP1APPMAPTKDM4EALDH1A1
SCHEMBL3799703 0.81 FBP1 (0.58) FBP1APPMAPTKDM4EALDH1A1
SCHEMBL3109674 0.81 FBP1 (0.61) FBP1APPMAPTKDM4EALDH1A1
SCHEMBL4631977 0.79 FBP1 (0.54) FBP1APPMAPTKDM4EALDH1A1
SCHEMBL28247791 0.79 FBP1 (0.54) FBP1APPMAPTKDM4EALDH1A1
SCHEMBL4631972 0.79 FBP1 (0.54) FBP1APPMAPTKDM4EALDH1A1
SCHEMBL3852033 0.78 FBP1 (0.58) FBP1APPMAPTKDM4EALDH1A1
SCHEMBL8856360 0.78 FBP1 (0.68) FBP1APPMAPTKDM4EALDH1A1
SCHEMBL8856356 0.78 FBP1 (0.68) FBP1APPMAPTKDM4EALDH1A1
SCHEMBL3852031 0.78 FBP1 (0.58) FBP1APPMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed