Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | EYA2 | O00167 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562613 | 0.84 | AKR1B1 (0.44) | CA12CA9CA2TSHRTDP1 | |
| SCHEMBL41505 | 0.84 | CA12 (0.55) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL30241145 | 0.83 | CA12 (0.44) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL6636451 | 0.82 | — | — | |
| Bromide SCHEMBL11753648 | 0.81 | CA12 (0.52) | CA12CA9CA2TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL10822973 | 0.81 | CA12 (0.52) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL5080836 | 0.81 | CA12 (0.43) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL28206109 | 0.81 | CA12 (0.43) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL331800 | 0.79 | — | — | |
| SCHEMBL8891629 | 0.79 | LMNA (0.40) | CA12CA9TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069877-A | The composition containing polycarbodiimide and amino-compound for treatment of keratinous substrates | 欧莱雅 | 2018-12-21 | — | — | CN | disclosed |
| EP-1924292-A2 | COMPOSITIONS AND METHODS FOR THE INTRAOCULAR TRANSPORT OF THERAPEUTIC AGENTS | Allergan, Inc. (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007037849-A2 | COMPOSITIONS AND METHODS FOR THE INTRAOCULAR TRANSPORT OF THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2007-04-05 | — | — | WO | disclosed |