Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632278 | 0.91 | PTPN11 (0.55) | PTPN11SLC6A9PLK1PDE4DMAPT | |
| SCHEMBL4601747 | 0.85 | PTPN11 (0.69) | PTPN11PPARDPPARASLC6A9PLK1 | |
| SCHEMBL14611096 | 0.82 | PTPN11 (0.58) | PTPN11SLC6A9MAPTHSD17B10CREBBP | |
| SCHEMBL4600952 | 0.78 | PTPN11 (0.85) | PTPN11PPARDPPARASLC6A9CREBBP | |
| SCHEMBL14610445 | 0.78 | PTPN11 (0.55) | PTPN11SLC6A9PDE4DMAPTHSD17B10 | |
| SCHEMBL14610792 | 0.77 | IKBKB (0.56) | PTPN11SLC6A9PDE4DMAPTHSD17B10 | |
| SCHEMBL14610866 | 0.77 | PTPN11 (0.51) | PTPN11MAPTHSD17B10FLT3MEN1 | |
| SCHEMBL14610581 | 0.77 | PTPN11 (0.51) | PTPN11SLC6A9PDE4DMAPTHSD17B10 | |
| SCHEMBL4600786 | 0.76 | PTPN11 (0.73) | PTPN11SLC6A9CREBBPFNTAFNTB | |
| SCHEMBL14610802 | 0.76 | PTPN11 (0.50) | PTPN11PDE4DMAPTHSD17B10PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |