Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632275 | 0.91 | PTPN11 (0.55) | PTPN11PLK1PDE4DCREBBPSLC6A9 | |
| SCHEMBL4601747 | 0.89 | PTPN11 (0.69) | PTPN11PLK1CREBBPSLC6A9MEN1 | |
| SCHEMBL14611096 | 0.87 | PTPN11 (0.58) | PTPN11CREBBPSLC6A9MKNK1MKNK2 | |
| SCHEMBL14610445 | 0.83 | PTPN11 (0.55) | PTPN11PDE4DSLC6A9MKNK1MKNK2 | |
| SCHEMBL14610792 | 0.82 | IKBKB (0.56) | PTPN11PDE4DSLC6A9MKNK1MKNK2 | |
| SCHEMBL14610581 | 0.82 | PTPN11 (0.51) | PTPN11PDE4DSLC6A9FYNMKNK1 | |
| SCHEMBL14610866 | 0.82 | PTPN11 (0.51) | PTPN11MKNK1MKNK2MAPTMEN1 | |
| SCHEMBL14610582 | 0.81 | PTPN11 (0.50) | PTPN11SLC6A9MKNK1MKNK2MAPT | |
| SCHEMBL14610802 | 0.81 | PTPN11 (0.50) | PTPN11PDE4DMKNK1MKNK2MAPT | |
| SCHEMBL14610583 | 0.80 | PTPN11 (0.54) | PTPN11PDE4DMKNK1MKNK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |