⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20240360 | 0.78 | LMNA (0.34) | — | |
| SCHEMBL5078432 | 0.78 | LMNA (0.41) | — | |
| SCHEMBL17713656 | 0.76 | LMNA (0.31) | — | |
| SCHEMBL21899858 | 0.73 | LMNA (0.33) | — | |
| SCHEMBL17963567 | 0.73 | LMNA (0.33) | — | |
| SCHEMBL4633549 | 0.73 | — | — | |
| SCHEMBL17028505 | 0.72 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL4407329 | 0.72 | HPGD (0.50) | — | |
| SCHEMBL29068365 | 0.72 | — | — | |
| SCHEMBL28105049 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924572-A1 | REGIOSELECTIVE PROCESS FOR PREPARING BENZIMIDAZOLE THIOPHENES | SmithKline Beecham Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007030366-A1 | REGIOSELECTIVE PROCESS FOR PREPARING BENZIMIDAZOLE THIOPHENES | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-15 | — | — | WO | disclosed |